False-positive ELISA reactivity to hepatitis B virus surface antigen (HBsAg)

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False-positive ELISA reactivity to hepatitis B virus surface antigen (HBsAg)

It is claimed that the possibility of non-specific reactions in ELISA tests for HBsAg has been substantially eliminated (1), though like any other highly sensitive immune test system, ELISA does still have the potential of yielding false-positive reactions. Such reactivity in the hepatitis B virus (HBV) hyperendemic focus of the Gizan Area of Saudi Arabia was encountered using a two-titer test ...

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Hepatitis B virus surface antigen (HBsAg)-positive and HBsAg-negative hepatitis B virus infection among mother-teenager pairs 13 years after neonatal hepatitis B virus vaccination.

It is unclear whether a mother who is negative for hepatitis B virus surface antigen (HBsAg) but positive for hepatitis B virus (HBV) is at potential risk for mother-to-child transmission of HBV. This study, using a paired mother-teenager population, aimed to assess whether maternal HBsAg-negative HBV infection ((hn)HBI) is a significant source of child HBV infection (HBI). A follow-up study wi...

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False positive Hepatitis B Surface Antigen due to recent vaccination.

OBJECTIVE Hepatitis B is the most common viral hepatitis, potentially life threatening, with long term complications. Currently, vaccine is the most effective tool against hepatitis B infection. It is worthwhile mentioning that due to rampant use of hepatitis B vaccine (HBV), there have been concerns about hepatitis B surface antigen (HBsAg) reactivity. This article aims to report the false pos...

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ELISA for Quantitative Determination of Hepatitis B Virus Surface Antigen

Several studies have reported a good correlation between levels of serum hepatitis B virus surface antigen (HBsAg) and covalently closed circular DNA (cccDNA) before and after antiviral therapy. As a result, the quantification of HBsAg levels has attracted much attention in recent years as an important approach to evaluate viral activity. In this study, mAbs against HBsAg were generated and 9 m...

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Incidence of Hepatitis B virus Surface Antigen (HBsAg) Mutations in Naïve Treated of Chronic Carriers from Tehran Metropolis, Iran

Abstract Background: Naturally occurred hepatitis B virus (HBV) with surface mutations in a variety of chronic hepatitis B (CHB) patients who have received no vaccine or HBIG bearing substitutions in surface protein, have been reported. Objectives: Current knowledge concerning the prevalence of these naturally occurring surface antigen mutations among Iranian carriers is limited. Patients and M...

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ژورنال

عنوان ژورنال: Infection

سال: 1986

ISSN: 0300-8126,1439-0973

DOI: 10.1007/bf01643484